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Table 2 Association of AC1/AC2 subgroups in external AC data sets with smoking history

From: Relation between smoking history and gene expression profiles in lung adenocarcinomas

Data set Nbr NS/smokers* Nbr NS/CS/FS* Nbr NS classified as AC1 % smokers classified as AC1 (All/CS/FS) Fisher’s exact test P-value **
DCC 49/300 49/32/268 45 (92%) 53/31/55 4 × 10−8/0.01
GSE10072 16/42 16/24/18 15 (94%) 55/46/67 0.005/0.22
GSE12667 8/43 8/18/25 8 (100%) 49/33/60 0.007/0.12
Beer et al. 9/72 9/NA/NA 8 (89%) 53/NA/NA 0.07/NA
GSE11969 45/45 45/NA/NA 37 (82%) 58/NA/NA 0.02/NA
GSE32863 29/29 29/29/0 23 (79%) 38/38/NA 0.003/NA
  1. * NS: never-smoker, CS: current smoker, FS: former smoker.
  2. ** Calculated from a 2×2 contingency table summarizing number of never-smokers and smokers for each AC subgroup (first p-value), or number of CS and FS for each AC subgroup (second p-value).