Figure 3

BioNet module. BioNet module annotated with selected KEGG pathways and GO terms obtained from functional enrichment analysis. Differentially expressed genes (P < 0.05) are indicated with a red circle (up-regulated in response to Flovent treatment) or a blue circle (down-regulated in response to Flovent treatment). A red label indicates a gene annotated in GO (biological process) with transcription factor activity. Grey circles indicate genes not expressed (based on XIST filtering - see Methods), which are connected to other genes through gray dashed lines.