Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients

Table 1 Patient demographics

Characteristics	All patients	Patients with	Patients without	P value
		hypersensitivity	hypersensitivity
Cohort 1
Number (n)	171	39	132
Sex, % male	89%	95%	89%	0.12
Age (years)	38 ± 9	38 ± 11	37 ± 8	0.55
Race, % Caucasian	74%	77%	73	0.68
Cohort 2
Number (n)	249	63	186
Sex, % male	89%	81%	92%	0.016
Age (years)	36 ± 8	34 ± 7	37 ± 8	0.014
Race, % Caucasian	78%	79%	77%	0.86
Cohort 1 + cohort 2
Number (n)	420	102	318
Sex, % male	92%	92%	92%	1
Age (years)	37 ± 8	36 ± 9	37 ± 8	0.47
Race, % Caucasian	86%	87%	86%	0.86

ISSN: 1755-8794