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Table 2 Clinical characteristics of breast cancer study cohort

From: Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles

   Overall TNBC ER+ Her2+ p-values
       TNBC vs. ER+ TNBC vs. Her2+ ER+ vs. Her2+
n   20 7 7 6    
Age at diagnosis mean ± standard deviation 52 ± 16 47 ± 14 59 ± 18 49 ± 16 0.21 0.83 0.33
Ethnicity         
Caucasian 10 3 5 2 0.59 1 0.56
African American 9 4 2 3
Asian 1 0 0 1    
Invasive carcinoma histology        
  ductal 14 7 3 6 0.07 1 0.19
  lobular 6 0 4 0
Tumor size (cm) mean ± standard deviation 4.8 ± 4.2 3.0 ± 1.1 4.9 ± 2.5 5.7 ± 7.4 0.06 0.35 0.81
T1 <2 cm 4 1 1 2    
T2 2.1 - 5 cm 10 6 2 2    
T3 >5 cm 6 0 4 2    
Tumor grade         
I 0 0 0 0    
II 3 1 3 0 0.03 1 0.03
III 11 6 0 4
not assessed 6 0 4 2    
No. of involved axilla node(s) mean ± standard deviation 5.5 ± 7.8 4.1 ± 8.6 6.4 ± 8.4 6.0 ± 7.0 0.10 0.56 0.52
  0 8 5 1 2    
1-3 4 0 4 0    
4-9 3 1 0 1    
>9 4 1 2 2    
not assessed 1 0 0 1    
Receptor status        
  ER+ 8 0 7 1    
PR+ 7 0 7 0    
Her2+ 6 0 0 6