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Table 2 Clinical characteristics of breast cancer study cohort

From: Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles

  

Overall

TNBC

ER+

Her2+

p-values

      

TNBC vs. ER+

TNBC vs. Her2+

ER+ vs. Her2+

n

 

20

7

7

6

   

Age at diagnosis mean ± standard deviation

52 ± 16

47 ± 14

59 ± 18

49 ± 16

0.21

0.83

0.33

Ethnicity

        

Caucasian

10

3

5

2

0.59

1

0.56

African American

9

4

2

3

Asian

1

0

0

1

   

Invasive carcinoma histology

       
 

ductal

14

7

3

6

0.07

1

0.19

 

lobular

6

0

4

0

Tumor size (cm) mean ± standard deviation

4.8 ± 4.2

3.0 ± 1.1

4.9 ± 2.5

5.7 ± 7.4

0.06

0.35

0.81

T1

<2 cm

4

1

1

2

   

T2

2.1 - 5 cm

10

6

2

2

   

T3

>5 cm

6

0

4

2

   

Tumor grade

        

I

0

0

0

0

   

II

3

1

3

0

0.03

1

0.03

III

11

6

0

4

not assessed

6

0

4

2

   

No. of involved axilla node(s) mean ± standard deviation

5.5 ± 7.8

4.1 ± 8.6

6.4 ± 8.4

6.0 ± 7.0

0.10

0.56

0.52

 

0

8

5

1

2

   

1-3

4

0

4

0

   

4-9

3

1

0

1

   

>9

4

1

2

2

   

not assessed

1

0

0

1

   

Receptor status

       
 

ER+

8

0

7

1

   

PR+

7

0

7

0

   

Her2+

6

0

0

6

   
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BMC Medical Genomics

ISSN: 1755-8794

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