Table 4 Characteristics of gene sets in publications where whole microarray data were unavailable
From: Integrative analysis of neuroblastoma and pheochromocytoma genomics data
Study | Number and distribution of samples | Gene list |
|---|---|---|
Asgharzadeh et al., 2006 [35] | 102 NB | 55 gene model for the prediction of high molecular risk NB |
Berwanger et al., 2002 [36] | Stage 1: 19, stage 4: 21 NB | 36 genes differently expressed between stage 1 and stage 4 NB |
Fischer et al., 2010 [40] | 81 unfavorable, 8 favorable NB, without 11q aberration | 163 genes differently expressed between favorable and unfavorable NB |
Oberthuer et al., 2006 [42] | 251 NB, among these 77 was used to construction of a gene expression–based classifier and 177 to validate it | 60 genes with higher than 2-fold expression changes from 144 gene predictor of favorable and unfavorable NB |
Oberthuer et al., 2007 [33] | 79 favorable and 48 unfavorable NB | 5 genes with higher than 2-fold expression changes from 349 gene predictor of favorable and unfavorable NB |
Ohira et al., 2005 [34] | 136 NB | 41 top-ranked genes used for prediction of 2 year and 5 year prognosis of NB |
Schramm et al., 2005 [31] | 59 MYCN-non-amplified, 9 MYCN-amplified NB | 28 top-ranked genes to discriminate MYCN-non-amplified and MYCN-amplified NB |
|  | Stage 1: 20, stage 2: 16, stage 3:7, stage 4: 15, stage 4S: 10 NB | 30 top-ranked genes to discriminate stage 1–2 and stage 3–4 NB |
| Â | Â | 22 top-ranked genes to discriminate stage 4S and stage 4 NB |
Takita et al., 2004 [43] | stage 1: 9, stage 2: 4, stage 4: 6, stage 4S: 1 NB | 60 top-ranked genes to discriminate stage 1–2 and stage 4 NB |
Thorell et al., 2009 [44] | 16 favorable and 15 unfavorable NB | 81 genes differently expressed between favorable and unfavorable NB, validated by QRT-PCR |
Vermeulen et al., 2009 [45] | 579 NB | 59 prognostic genes for high risk NB |
Brown et al., 2008 [37] | 12 MEN2A, 11 VHL PCC | 17 genes differently expressed between MEN2A and VHL by SAM (fold change: 2-fold, delta lower than 0.05) |
Eisenhofer et al., 2004 [38] | 7 MEN2A, 12 VHL PCC | 493 genes differently expressed between MEN2A and VHL PCC |
Eisenhofer et al., 2008 [39] | 32 MEN2A, 47 VHL PCC | 42 selected pathway components differently expressed between MEN2A and VHL PCC |
Huynh et al., 2006 [41] | 13 MEN2A, 18 VHL PCC | 15 genes selected differently expressed genes between MEN2A and VHL PCC |
López-Jiménez et al., 2010 [32] | 8 SDHB, 1 SDHC, 4 SDHD, 15 VHL, 17 RET, 4 NF1 | 444 genes differently expressed between VHL/SDH and RET/NF1 PCC |