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Table 4 Characteristics of gene sets in publications where whole microarray data were unavailable

From: Integrative analysis of neuroblastoma and pheochromocytoma genomics data

Study Number and distribution of samples Gene list
Asgharzadeh et al., 2006 [35] 102 NB 55 gene model for the prediction of high molecular risk NB
Berwanger et al., 2002 [36] Stage 1: 19, stage 4: 21 NB 36 genes differently expressed between stage 1 and stage 4 NB
Fischer et al., 2010 [40] 81 unfavorable, 8 favorable NB, without 11q aberration 163 genes differently expressed between favorable and unfavorable NB
Oberthuer et al., 2006 [42] 251 NB, among these 77 was used to construction of a gene expression–based classifier and 177 to validate it 60 genes with higher than 2-fold expression changes from 144 gene predictor of favorable and unfavorable NB
Oberthuer et al., 2007 [33] 79 favorable and 48 unfavorable NB 5 genes with higher than 2-fold expression changes from 349 gene predictor of favorable and unfavorable NB
Ohira et al., 2005 [34] 136 NB 41 top-ranked genes used for prediction of 2 year and 5 year prognosis of NB
Schramm et al., 2005 [31] 59 MYCN-non-amplified, 9 MYCN-amplified NB 28 top-ranked genes to discriminate MYCN-non-amplified and MYCN-amplified NB
  Stage 1: 20, stage 2: 16, stage 3:7, stage 4: 15, stage 4S: 10 NB 30 top-ranked genes to discriminate stage 1–2 and stage 3–4 NB
   22 top-ranked genes to discriminate stage 4S and stage 4 NB
Takita et al., 2004 [43] stage 1: 9, stage 2: 4, stage 4: 6, stage 4S: 1 NB 60 top-ranked genes to discriminate stage 1–2 and stage 4 NB
Thorell et al., 2009 [44] 16 favorable and 15 unfavorable NB 81 genes differently expressed between favorable and unfavorable NB, validated by QRT-PCR
Vermeulen et al., 2009 [45] 579 NB 59 prognostic genes for high risk NB
Brown et al., 2008 [37] 12 MEN2A, 11 VHL PCC 17 genes differently expressed between MEN2A and VHL by SAM (fold change: 2-fold, delta lower than 0.05)
Eisenhofer et al., 2004 [38] 7 MEN2A, 12 VHL PCC 493 genes differently expressed between MEN2A and VHL PCC
Eisenhofer et al., 2008 [39] 32 MEN2A, 47 VHL PCC 42 selected pathway components differently expressed between MEN2A and VHL PCC
Huynh et al., 2006 [41] 13 MEN2A, 18 VHL PCC 15 genes selected differently expressed genes between MEN2A and VHL PCC
López-Jiménez et al., 2010 [32] 8 SDHB, 1 SDHC, 4 SDHD, 15 VHL, 17 RET, 4 NF1 444 genes differently expressed between VHL/SDH and RET/NF1 PCC