Table 3 Ten most significant KEGG and GO categories enriched among the genes displaying alternative exon usage
Source | Category | Gene Count1 | FDR P-value2 |
|---|---|---|---|
KEGG Pathway | (hsa04510) focal adhesion | 86 | 3.2E-21 |
(hsa04512) ecm-receptor interaction | 51 | 8.5E-20 | |
(hsa02010) abc transporters | 30 | 2.5E-12 | |
(hsa04810) regulation of actin cytoskeleton | 66 | 1.7E-07 | |
(hsa05412) arrhythmogenic right ventricular cardiomyopathy | 32 | 5.9E-06 | |
(hsa05414) dilated cardiomyopathy | 37 | 1.3E-06 | |
(hsa04070) phosphatidylinositol signaling system | 31 | 1.2E-05 | |
(hsa05222) small cell lung cancer | 31 | 3.6E-04 | |
(hsa05410) hypertrophic cardiomyopathy | 32 | 1.3E-04 | |
| Â | (hsa05200) pathways in cancer | 73 | 3.0E-02 |
GO Biological Process | (GO:0051056) regulation of small GTPase mediated signal transduction | 105 | 0.055 |
(GO:0022610) biological adhesion | 197 | 2.7E-22 | |
(GO:0007155) cell adhesion | 197 | 2.3E-22 | |
(GO:0046578) regulation of Ras protein signal transduction | 79 | 5.0E-15 | |
(GO:0035023) regulation of Rho protein signal transduction | 51 | 1.7E-15 | |
(GO:0007010) cytoskeleton organization | 129 | 1.3E-15 | |
(GO:0030029) actin filament-based process | 85 | 2.3E-14 | |
(GO:0007018) microtubule-based movement | 51 | 2.1E-12 | |
(GO:0016568) chromatin modification | 89 | 1.9E-12 | |
| Â | (GO:0051276) chromosome organization | 132 | 1.4E-12 |
GO Molecular Function | (GO:0030554) adenyl nucleotide binding | 451 | 9.9E-59 |
(GO:0005524) ATP binding | 433 | 2.2E-59 | |
(GO:0032559) adenyl ribonucleotide binding | 437 | 2.0E-59 | |
(GO:0001882) nucleoside binding | 456 | 6.3E-58 | |
(GO:0001883) purine nucleoside binding | 451 | 1.5E-56 | |
(GO:0017076) purine nucleotide binding | 480 | 5.2E-44 | |
(GO:0032555) purine ribonucleotide binding | 466 | 2.9E-44 | |
(GO:0032553) ribonucleotide binding | 466 | 2.9E-44 | |
(GO:0000166) nucleotide binding | 523 | 7.4E-39 | |
| Â | (GO:0003774) motor activity | 86 | 1.3E-34 |