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Table 1 Characteristics of the patients.

From: Routine use of microarray-based gene expression profiling to identify patients with low cytogenetic risk acute myeloid leukemia: accurate results can be obtained even with suboptimal samples

Covariates Overall APLs t(8;21)-AMLs inv(16)-AMLs NK-AMLs
Patients N = 97 N = 18 N = 19 N = 29 N = 31
Gender      
Males 44 7 13 15 9
Females 53 11 6 14 22
Age at diagnosis      
Median (years) 54 56 53 38 60
Range 18-87 19-87 18-84 18-70 25-78
Leukocytosis at diagnosis      
WBC ≥ 30 G/L 39 2 6 12 19
FAB classification      
M1 or M2 45 0 18 6 21
M3 18 18 0 0 0
M4 or M5 34 0 0 24 10
Cytogenetics      
Expected anomaly* 62 16 19 27 0
Normal karyotype 34 2 0 1 31
Karyotype failure 1 0 0 1 0
Gene mutations      
FLT3-ITD$ 19 2 1 2 14
FLT3-D835& 7 2 2 2 1
NPM1 18 0 0 1 17
CEBPA (mono-allelic) 4 0 2 1 1
  1. WBC, white blood cells. * t(15;17), t(8;21), inv(16) or t(16;16) for APL, t(8;21)-AML and inv(16)-AML, respectively detected. $ Internal tandem duplication. &Mutation Asp835 of the tyrosine kinase domain.