|
SNPs(gene)
|
Haplotype
|
Control (n,%)
|
Case (n,%)
|
χ2
|
P value
|
OR
|
OR(95%CI)
|
|---|
|
rs2241718(TGF-β1)
|
GC
|
107(50)
|
83(25)
|
36.0947
|
1.88×10
-9
|
0.33
|
0.23-0.48
|
|
rs6957(CDC97)
|
Non-GC
|
106(50)
|
248(75)
| | | | |
| |
GT
|
107(50)
|
83(25)
|
36.0947
|
1.88×10
-9
|
0.33
|
0.23-0.48
|
| |
Non-GT
|
106(50)
|
248(75)
| | | | |
|
rs1800469(TGF-β1)
|
TG
|
111(52)
|
159(48)
|
0.8615
|
0.3533
|
0.85
|
0.60-1.20
|
|
rs2241712(TGF-β1)
|
Non-TG
|
102(48)
|
172(52)
| | | | |
| |
CA
|
94(44)
|
162(49)
|
1.2041
|
0.2725
|
1.21
|
0.86-1.71
|
| |
Non-CA
|
119(56)
|
169(51)
| | | | |
|
rs1205(CRP)
|
TT
|
130(61)
|
172(52)
|
4.3163
|
0.0377
|
0.69
|
0.49-0.98
|
|
rs2808630(CRP)
|
Non-TT
|
83(39)
|
159(48)
| | | | |
| |
CC
|
32(15)
|
60(18)
|
0.8883
|
0.3459
|
1.25
|
0.78-2.0
|
| |
Non-CC
|
181(85)
|
271(82)
| | | | |
| |
CT
|
51(24)
|
96(29)
|
1.6822
|
0.1946
|
1.30
|
0.87-1.92
|
| |
Non-CT
|
162(76)
|
235(71)
| | | | |
- The p value with bold letters indicate those allele frequencies with significant differences between COPD and controls.
