Skip to main content

Advertisement

Table 6 Haplotypes of the CRP and TGF-β1 gene

From: Association of genetic polymorphisms with chronic obstructive pulmonary disease in the Chinese Han population: a case–control study

SNPs(gene) Haplotype Control (n,%) Case (n,%) χ2 P value OR OR(95%CI)
rs2241718(TGF-β1) GC 107(50) 83(25) 36.0947 1.88×10 -9 0.33 0.23-0.48
rs6957(CDC97) Non-GC 106(50) 248(75)     
  GT 107(50) 83(25) 36.0947 1.88×10 -9 0.33 0.23-0.48
  Non-GT 106(50) 248(75)     
rs1800469(TGF-β1) TG 111(52) 159(48) 0.8615 0.3533 0.85 0.60-1.20
rs2241712(TGF-β1) Non-TG 102(48) 172(52)     
  CA 94(44) 162(49) 1.2041 0.2725 1.21 0.86-1.71
  Non-CA 119(56) 169(51)     
rs1205(CRP) TT 130(61) 172(52) 4.3163 0.0377 0.69 0.49-0.98
rs2808630(CRP) Non-TT 83(39) 159(48)     
  CC 32(15) 60(18) 0.8883 0.3459 1.25 0.78-2.0
  Non-CC 181(85) 271(82)     
  CT 51(24) 96(29) 1.6822 0.1946 1.30 0.87-1.92
  Non-CT 162(76) 235(71)     
  1. The p value with bold letters indicate those allele frequencies with significant differences between COPD and controls.