Table 6 Haplotypes of the CRP and TGF-β1 gene
SNPs(gene) | Haplotype | Control (n,%) | Case (n,%) | χ2 | P value | OR | OR(95%CI) |
|---|---|---|---|---|---|---|---|
rs2241718(TGF-β1) | GC | 107(50) | 83(25) | 36.0947 | 1.88×10 -9 | 0.33 | 0.23-0.48 |
rs6957(CDC97) | Non-GC | 106(50) | 248(75) | ||||
GT | 107(50) | 83(25) | 36.0947 | 1.88×10 -9 | 0.33 | 0.23-0.48 | |
Non-GT | 106(50) | 248(75) | |||||
rs1800469(TGF-β1) | TG | 111(52) | 159(48) | 0.8615 | 0.3533 | 0.85 | 0.60-1.20 |
rs2241712(TGF-β1) | Non-TG | 102(48) | 172(52) | ||||
CA | 94(44) | 162(49) | 1.2041 | 0.2725 | 1.21 | 0.86-1.71 | |
Non-CA | 119(56) | 169(51) | |||||
rs1205(CRP) | TT | 130(61) | 172(52) | 4.3163 | 0.0377 | 0.69 | 0.49-0.98 |
rs2808630(CRP) | Non-TT | 83(39) | 159(48) | ||||
CC | 32(15) | 60(18) | 0.8883 | 0.3459 | 1.25 | 0.78-2.0 | |
Non-CC | 181(85) | 271(82) | |||||
CT | 51(24) | 96(29) | 1.6822 | 0.1946 | 1.30 | 0.87-1.92 | |
Non-CT | 162(76) | 235(71) |