Table 1 Frequencies of LOH, LOI and MOI in human ovarian cancers.
(A) Ovarian cancer tissues | ||||||||
|---|---|---|---|---|---|---|---|---|
| Â | H19/ R sal | IGF2/ Apal | KCNQ1/ Smal | LIT1/ R sal | GTL2/ T aal | PEG1/ AFlll | PEG3/ Mnll | NDN/ Mbol |
Heterozygosity | 58.5 (41/70) | 47.1 (33/70) | 55.5 (40/72) | 16.2 (12/74) | 58.3 (42/72) | 50.0 (37/74) | 34.2 (25/73) | 41.8 (31/74) |
LOH | 4.8 (2/41) | 9.0 (3/33) | 5.0 (2/40) | 0.0 (0/12) | 7.1 (3/42) | 8.1 (3/37) | 4.0 (1/25) | 0.0 (0/31) |
LOI | 29.2 (12/41) | 45.4 (15/33) | 12.5 (5/40) | 16.6 (2/12) | 23.8 (10/42) | 45.9 (17/37) | 8.0 (2/25) | 6.4 (2/31) |
MOI | 56.0 (23/41) | 33.3 (11/33) | 77.5 (31/40) | 83.3 (10/12) | 66.6 (28/42) | 45.9 (17/37) | 84.0 (21/25) | 93.5 (29/31) |
ND | 9.7 (4/41) | 12.1 (4/33) | 5.0 (2/40) | 0.0 (0/12) | 2.3 (1/42) | 0.0 (0/37) | 4.0 (1/25) | 0.0 (0/31) |
(B) Cell lines | ||||||||
Heterozygosity | 19.0 (4/21) | 14.2 (3/21) | 33.3 (7/21) | 14.39 (3/21) | 23.8 (5/21) | 42.8 (9/21) | 23.8 (5/21) | 23.8 (5/21) |
LOI | 0/4 | 2/3 | 3/7 | 1/3 | 2/5 | 3/9 | 0/5 | 0/5 |
MOI | 4/4 | 1/3 | 4/7 | 2/3 | 3/5 | 6/9 | 5/5 | 5/5 |