|
Target ID
|
KDM5C AVG Beta
|
Control AVG Beta
|
VUS AVG Beta
|
p-value
|
delta beta
|
delta Z
|
SYMBOL
|
DISTANCE TO TSS
|
|---|
|
cg02630888
|
0.41
|
0.89
|
0.91
|
9.98E-08
|
−0.48
|
2.03
|
FBXL5
|
−807
|
|
cg03387723
|
0.26
|
0.71
|
0.73
|
9.98E-08
|
−0.45
|
2.01
|
SCMH1
|
−676
|
|
cg16743289
|
0.24
|
0.52
|
0.53
|
9.98E-08
|
−0.28
|
2.02
|
CACYBP
|
−427
|
|
cg06736444
|
0.50
|
0.78
|
0.77
|
9.98E-08
|
−0.28
|
1.90
|
SRRM2
|
−861
|
|
cg22809047
|
0.31
|
0.59
|
0.54
|
9.98E-08
|
−0.27
|
1.91
|
RPL31
|
−490
|
|
cg19884658
|
0.55
|
0.77
|
0.74
|
9.98E-08
|
−0.23
|
1.98
|
KLHL21
|
−1,339
|
|
cg14719055
|
0.20
|
0.42
|
0.37
|
9.98E-08
|
−0.23
|
1.92
|
RBBP7
|
−1,218
|
|
cg16604218
|
0.09
|
0.31
|
0.35
|
9.98E-08
|
−0.22
|
1.84
|
EIF2B3
|
−349
|
|
cg20318748
|
0.07
|
0.29
|
0.18
|
9.98E-08
|
−0.22
|
1.95
|
NANP
|
−564
|
|
cg03621001
|
0.46
|
0.67
|
0.77
|
9.98E-08
|
−0.21
|
1.91
|
RAB8A
|
−771
|
|
cg00328227
|
0.08
|
0.28
|
0.30
|
9.98E-08
|
−0.2
|
1.95
|
C1orf59
|
−177
|
|
cg05072008
|
0.13
|
0.33
|
0.37
|
9.98E-08
|
−0.2
|
1.86
|
FIGNL1
|
−599
|
|
cg03221914
|
0.50
|
0.69
|
0.70
|
9.98E-08
|
−0.2
|
1.82
|
HIST1H2AJ
|
−813
|
- VUS is p.R1546Q variant of unknown significance, AVG beta is mean beta value for each of three groups, delta beta is differences between mean of KDM5C mutations cases (N = 10) and controls (N = 19). Delta Z is delta beta divided by standard deviation of combined cases and controls data. All 13 CpG sites were located within CpG islands.
