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Table 1 GRAIL analysis of associations to over- and under-expressed pathways of GBMs

From: Genome-wide associations of signaling pathways in glioblastoma multiforme

Over-expressed pathways Under-expressed pathways
Tag-locus Chr. Npw Gene Tag-locus Chr. Npw Gene
SNP_A-1731917 10 13 PTEN SNP_A-1705677 4 17 TMPRSS11A
SNP_A-1656043 7 10 EGFR SNP_A-1668058 4 11 BMPR1B
SNP_A-1742783 10 8 PLCE1 SNP_A-1654343 4 9 EGF
SNP_A-1662548 10 8 HABP2 SNP_A-1669535 4 9 ABCG2
SNP_A-1686878 10 8 FAS SNP_A-1751745 4 8 ABCG2
SNP_A-1754053 10 7 PIK3AP1 SNP_A-1705909 4 8 MAPK10
SNP_A-1720407 7 6 EGFR SNP_A-1741853 1 6 C1orf64
SNP_A-1724476 10 6 C10orf46 SNP_A-1706913 1 5 PRDM2
SNP_A-1730020 10 5 CCDC7 SNP_A-1673860 16 5 CDH13
SNP_A-1731857 10 5 BAG3 SNP_A-1697048 16 3 CDH13
SNP_A-1679064 10 4 HABP2 SNP_A-1749105 12 3 EPS8
SNP_A-1747199 7 3 EPHB6 SNP_A-1728851 10 3 MGMT
SNP_A-1674301 20 3 RBL1 SNP_A-1716085 1 3 STMN1
SNP_A-1721335 7 3 CAV2 SNP_A-1652906 4 2 IGFBP7
SNP_A-1683894 7 3 GHRHR SNP_A-1658232 1 2 STMN1
SNP_A-1661029 7 2 NOS3 SNP_A-1721335 7 2 CAV2
SNP_A-1694743 4 2 PI4K2B SNP_A-1651620 11 2 FGF19
SNP_A-1732612 17 2 NF1 SNP_A-1661013 16 2 CYLD
SNP_A-1695427 17 2 KSR1 SNP_A-1739981 12 2 KRAS
SNP_A-1741009 10 2 CCDC7 SNP_A-1655097 4 2 KDR
SNP_A-1720403 7 2 BRAF SNP_A-1750171 1 2 FRAP1
SNP_A-1745332 4 2 INPP4B SNP_A-1723196 3 2 BCL6
SNP_A-1747257 10 2 IL2RA SNP_A-1687110 1 2 C1orf64
SNP_A-1647840 10 2 RET SNP_A-1710047 20 2 JAG1
SNP_A-1663346 7 2 CDK6     
SNP_A-1728851 10 2 MGMT     
  1. We annotated tag-loci that were significantly associated with more than one over- or under-expressed pathways in GBMs with their corresponding genes (GRAIL P < 0.05).