Gene ontology (GO) analysis and significant functional genes. Left: Numbers of genes in the 6 representative profiles. Middle: significant functional categories and the number of genes in them. Each color represents one category and the size of each sector in a pie diagram is proportional to the number of genes in its category. Right: Merged functional categories in permissive “Pup”, “Bdown” and “PupBdown” cells and resistant “Pdown”, “Bup” and “PdownBup” cells.