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Table 3 Number of similar toxicological endpoints

From: Next-generation text-mining mediated generation of chemical response-specific gene sets for interpretation of gene expression data

Chemical name

CAS number

# similar general developmental toxicity endpoints

# similar morphological developmental toxicity endpoints

p-value

Metam-sodium

137-42-8

3

3

5.6e-03

Mepiquat chloride

24307-26-4

0

2

9.3e-03

Clomazone

81777-89-1

2

3

9.3e-03

6-Deisopropylatrazine

1007-28-9

0

2

9.3e-03

Zoxamide

156052-68-5

0

0

9.3e-03

Iprodione

36734-19-7

4

2

9.3e-03

Monosodium methane arsenate

2163-80-6

3

0

9.3e-03

Cyprodinil

121552-61-2

2

2

9.5e-03

Carfentrazone-ethyl

128639-02-1

0

1

1.3e-02

Primisulfuron-methyl

86209-51-0

1

3

1.3e-02

3-(3,5-Dichlorophenyl)-1,5-dimethyl-3-azabicyclo(3.1.0)hexane-2,4-dione

32809-16-8

0

0

1.7e-02

Bromadiolone

28772-56-7

1

0

1.7e-02

MGK 264

113-48-4

0

0

2.5e-02

Diniconazole

83657-24-3

3

3

2.5e-02

Difenoconazole

119446-68-3

3

1

2.5e-02

Fenpropathrin

39515-41-8

1

0

2.5e-02

Fenbuconazole

114369-43-6

4

1

2.5e-02

Bendiocarb

22781-23-3

2

0

2.5e-02

Dacthal

1861-32-1

1

0

2.5e-02

Fludioxonil

131341-86-1

0

2

2.5e-02

Mancozeb

8018-01-7

3

3

2.5e-02

Triadimenol

55219-65-3

0

3

2.5e-02

Myclobutanil

88671-89-0

2

1

2.5e-02

Cyproconazole

94361-06-5

2

2

2.9e-02

Fluroxypyr

69377-81-7

1

0

3.1e-02

Fluazifop-P-butyl

79241-46-6

2

4

3.5e-02

Ethametsulfuron methyl

97780-06-8

4

2

3.5e-02

Cyclanilide

113136-77-9

0

0

3.8e-02

EPTC

759-94-4

4

1

4.1e-02

Metaldehyde

108-62-3

1

0

4.1e-02

Cyhexatin

13121-70-5

3

0

4.1e-02

Pyrimethanil

53112-28-0

3

2

4.1e-02

Nitrapyrin

1929-82-4

1

1

4.7e-02

  1. Number of similar toxicological endpoints and false discovery rate-corrected p-values for chemicals predicted similar to the triazole gene expression data set using the weighted global test. Chemicals with a similar morphological developmental in vivo toxicity profile to triazoles are in bold.