Figure 2
From: Interplay between estrogen receptor and AKT in Estradiol-induced alternative splicing
ERα binding pattern to alternatively spliced genes in response to E2 treatment. ChIP-on-chip data of MCF-7p and MCF-7AKT cells and/or ChIP-seq of MCF-7 cells with or without E2 or tamoxifen treatment reveal ERα binding sites within or around alternatively spliced genes. Relative position of genes on respective chromosomes along with ERα binding site detected in treated cells (black bar) are shown. Black arrow indicates direction of the gene. Asterisk indicates ERα binding sites verified by ChIP-qPCR.