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Table 4 Pathway-specific transcription factor profile

From: Microarray characterization of gene expression changes in blood during acute ethanol exposure

A. p38-related TF* profile by cluster

Cluster

1

2

3

4

5

Transcription

NF-κB

   

NF-κB

Factors

SPI-1

 

SPI-1

 

SPI-1

  

ATF2

ATF2

ATF2

 
  

CREB1

CREB1

 

CREB1

    

ELK-1

ELK-1

   

JUN

JUN

 

B. Cluster-specific TF pathway profiles

Cluster

2

3

4

7

 

Pathway Membership

TLR4

Wnt, E2F

Apoptosis

STAT binding

 

Transcription

IRF3, 7

    

Factors

 

ETF2

   
  

LEF1/TCF7

   
   

FOXO3, 4

  
   

ELK-1

  
   

MYC

  
    

STAT1, 3, 5A

 
  1. *TF Transcription factors predicted by BIOBASE [43] to bind cluster members as defined in the text.