Figure 2

TGen outlier-group differentially expressed genes (Figure  4 , step 5). Differential expression was calculated using t-tests on log (base 2) expression values at FDR < 5%. A) Overlap of differentially expressed genes for the three outlier groups. B) Comparison of the log (base 2) expression levels of the two most differentially expressed genes in the neuron development pathway, SPON2 and FEZ1. Marginal density plots show the distributions of case (red) and control (blue) samples.