Table 1 Case/control outlier counts in outlier-enriched TGen pathways
Pathway | Case outliers | Control outliers | Fisher’s exact test P |
|---|---|---|---|
Neuron development | 20 / 70 (28.6%) | 2 / 60 (3.3%) | 9.97 × 10− 5 |
Nitric oxide signaling | 20 / 70 (28.6%) | 2 / 60 (3.3%) | 9.97 × 10− 5 |
Skeletal development | 19 / 70 (27.1%) | 2 / 60 (3.3%) | 2.03 × 10− 4 |
Total | 35 / 70 (50%) | 5 / 60 (8.3%) | 1.47 × 10− 7 |