Figure 2From: DNA methylation status of NKX2-5, GATA4 and HAND1in patients with tetralogy of fallot Median methylation levels for GATA4 in TOF patients and controls. (A) The schematic represents the distribution of the CpG site and CpG island in the GATA4 gene; (B) The sequence shown represents a 500 base pair fragment (positions -392 – 107) in the 5′-UTR of GATA4; (C) GATA4_M median methylation level. All of the values represent the median with the interquartile range. TSS, Transcription Start Sites; red vertical line, CpG sites; red thick bars, CpG islands; M,MassARRAY amplicon; The region between arrows, target amplicon. *p < 0.05, **p < 0.01, ***p < 0.001 (Mann–Whitney test).Back to article page