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Table 3 Pathways identified using the genes associated with ChIP-seq histone modification peaks for ASH and control

From: ChIP-seq in steatohepatitis and normal liver tissue identifies candidate disease mechanisms related to progression to cancer

KEGG pathway ENSEMBL_GENE_ID Gene name
Control
Glycine, serine and threonine metabolism ENSG00000092621 Phosphoglycerate dehydrogenase
  ENSG00000131471 Amine oxidase, copper containing 3 (vascular adhesion protein 1)
  ENSG00000168237 Glycerate kinase
  ENSG00000182199 Serine hydroxymethyltransferase 2 (mitochondrial)
  ENSG00000069535 Monoamine oxidase B
  ENSG00000145692 Betaine-homocysteine methyltransferase
  ENSG00000160200 Cystathionine-beta-synthase
  ENSG00000145020 Aminomethyltransferase
  ENSG00000023330 Aminolevulinate, delta-, synthase 1
  ENSG00000172482 Alanine-glyoxylate aminotransferase
Pyruvate metabolism ENSG00000076555 Acetyl-Coenzyme A carboxylase beta
  ENSG00000168291 Pyruvate dehydrogenase (lipoamide) beta
  ENSG00000154930 Acyl-CoA synthetase short-chain family member 1
  ENSG00000166816 Lactate dehydrogenase D
  ENSG00000173599 Pyruvate carboxylase
  ENSG00000063854 Hydroxyacylglutathione hydrolase
Fatty acid metabolism ENSG00000127884 Enoyl Coenzyme A hydratase, short chain, 1, mitochondrial
  ENSG00000162365 Cytochrome P450, family 4, subfamily A, polypeptide 22
  ENSG00000105607 Glutaryl-Coenzyme A dehydrogenase
  ENSG00000151726 Acyl-CoA synthetase long-chain family member 1
  ENSG00000187048 Cytochrome P450, family 4, subfamily A, polypeptide 11
  ENSG00000196344 Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
PPAR signaling pathway ENSG00000083807 Solute carrier family 27 (fatty acid transporter), member 5
  ENSG00000186350 Retinoid X receptor, alpha
  ENSG00000165269 Aquaporin 7
  ENSG00000162365 Cytochrome P450, family 4, subfamily A, polypeptide 22
  ENSG00000151726 Acyl-CoA synthetase long-chain family member 1
  ENSG00000118137 Apolipoprotein A-I
  ENSG00000187048 Cytochrome P450, family 4, subfamily A, polypeptide 11
  ENSG00000140284 Solute carrier family 27 (fatty acid transporter), member 2
Steroid biosynthesis ENSG00000052802 Sterol-C4-methyl oxidase-like
  ENSG00000109929 Sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
  ENSG00000116133 24-dehydrocholesterol reductase
  ENSG00000001630 Cytochrome P450, family 51, subfamily A, polypeptide 1
ASH
Pathways in cancer ENSG00000108091 Coiled-coil domain containing 6
  ENSG00000168040 Fas (TNFRSF6)-associated via death domain
  ENSG00000197461 Platelet-derived growth factor alpha polypeptide
  ENSG00000143816 Wingless-type MMTV integration site family, member 9A
  ENSG00000100644 Hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
  ENSG00000177885 Growth factor receptor-bound protein 2
  ENSG00000006451 v-ral simian leukemia viral oncogene homolog A (ras related)
  ENSG00000133101 Cyclin A1
  ENSG00000157404 Similar to Mast/stem cell growth factor receptor precursor (SCFR) (Proto-oncogene tyrosine-protein kinase Kit)Ta
  ENSG00000175305 Cyclin E2
  ENSG00000168036 Catenin (cadherin-associated protein), beta 1, 88 kDa
  ENSG00000147889 Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
  ENSG00000033800 Protein inhibitor of activated STAT, 1
  ENSG00000145675 Phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
  ENSG00000044115 Catenin (cadherin-associated protein), alpha 1, 102 kDa
  ENSG00000156427 Fibroblast growth factor 18
  ENSG00000135766 Egl nine homolog 1 (C. elegans)
  ENSG00000196591 Histone deacetylase 2
  ENSG00000138448 Integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  ENSG00000108379 Wingless-type MMTV integration site family, member 3
  ENSG00000104290 Frizzled homolog 3 (Drosophila)
  ENSG00000125084 Wingless-type MMTV integration site family, member 1
  ENSG00000102678 Fibroblast growth factor 9 (glia-activating factor)
  ENSG00000185920 Patched homolog 1 (Drosophila)
  ENSG00000111186 Wingless-type MMTV integration site family, member 5B
  ENSG00000161958 Fibroblast growth factor 11
  ENSG00000128602 Smoothened homolog (Drosophila)
  ENSG00000138795 Lymphoid enhancer-binding factor 1
  ENSG00000053747 Laminin, alpha 3
  ENSG00000056558 TNF receptor-associated factor 1
  ENSG00000131759 Retinoic acid receptor, alpha
  ENSG00000099942 v-crk sarcoma virus CT10 oncogene homolog (avian)-like
  ENSG00000139687 Retinoblastoma 1
  ENSG00000007968 E2F transcription factor 2
Basal cell carcinoma ENSG00000111186 Wingless-type MMTV integration site family, member 5B
  ENSG00000128602 Smoothened homolog (Drosophila)
  ENSG00000108379 Wingless-type MMTV integration site family, member 3
  ENSG00000138795 Lymphoid enhancer-binding factor 1
  ENSG00000168036 Catenin (cadherin-associated protein), beta 1, 88 kDa
  ENSG00000104290 Frizzled homolog 3 (Drosophila)
  ENSG00000125084 Wingless-type MMTV integration site family, member 1
  ENSG00000143816 Wingless-type MMTV integration site family, member 9A