Table 3 Pathways identified using the genes associated with ChIP-seq histone modification peaks for ASH and control
KEGG pathway | ENSEMBL_GENE_ID | Gene name |
|---|---|---|
Control | ||
Glycine, serine and threonine metabolism | ENSG00000092621 | Phosphoglycerate dehydrogenase |
| Â | ENSG00000131471 | Amine oxidase, copper containing 3 (vascular adhesion protein 1) |
| Â | ENSG00000168237 | Glycerate kinase |
| Â | ENSG00000182199 | Serine hydroxymethyltransferase 2 (mitochondrial) |
| Â | ENSG00000069535 | Monoamine oxidase B |
| Â | ENSG00000145692 | Betaine-homocysteine methyltransferase |
| Â | ENSG00000160200 | Cystathionine-beta-synthase |
| Â | ENSG00000145020 | Aminomethyltransferase |
| Â | ENSG00000023330 | Aminolevulinate, delta-, synthase 1 |
| Â | ENSG00000172482 | Alanine-glyoxylate aminotransferase |
Pyruvate metabolism | ENSG00000076555 | Acetyl-Coenzyme A carboxylase beta |
| Â | ENSG00000168291 | Pyruvate dehydrogenase (lipoamide) beta |
| Â | ENSG00000154930 | Acyl-CoA synthetase short-chain family member 1 |
| Â | ENSG00000166816 | Lactate dehydrogenase D |
| Â | ENSG00000173599 | Pyruvate carboxylase |
| Â | ENSG00000063854 | Hydroxyacylglutathione hydrolase |
Fatty acid metabolism | ENSG00000127884 | Enoyl Coenzyme A hydratase, short chain, 1, mitochondrial |
| Â | ENSG00000162365 | Cytochrome P450, family 4, subfamily A, polypeptide 22 |
| Â | ENSG00000105607 | Glutaryl-Coenzyme A dehydrogenase |
| Â | ENSG00000151726 | Acyl-CoA synthetase long-chain family member 1 |
| Â | ENSG00000187048 | Cytochrome P450, family 4, subfamily A, polypeptide 11 |
| Â | ENSG00000196344 | Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
PPAR signaling pathway | ENSG00000083807 | Solute carrier family 27 (fatty acid transporter), member 5 |
| Â | ENSG00000186350 | Retinoid X receptor, alpha |
| Â | ENSG00000165269 | Aquaporin 7 |
| Â | ENSG00000162365 | Cytochrome P450, family 4, subfamily A, polypeptide 22 |
| Â | ENSG00000151726 | Acyl-CoA synthetase long-chain family member 1 |
| Â | ENSG00000118137 | Apolipoprotein A-I |
| Â | ENSG00000187048 | Cytochrome P450, family 4, subfamily A, polypeptide 11 |
| Â | ENSG00000140284 | Solute carrier family 27 (fatty acid transporter), member 2 |
Steroid biosynthesis | ENSG00000052802 | Sterol-C4-methyl oxidase-like |
| Â | ENSG00000109929 | Sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like |
| Â | ENSG00000116133 | 24-dehydrocholesterol reductase |
| Â | ENSG00000001630 | Cytochrome P450, family 51, subfamily A, polypeptide 1 |
ASH | ||
Pathways in cancer | ENSG00000108091 | Coiled-coil domain containing 6 |
| Â | ENSG00000168040 | Fas (TNFRSF6)-associated via death domain |
| Â | ENSG00000197461 | Platelet-derived growth factor alpha polypeptide |
| Â | ENSG00000143816 | Wingless-type MMTV integration site family, member 9A |
| Â | ENSG00000100644 | Hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
| Â | ENSG00000177885 | Growth factor receptor-bound protein 2 |
| Â | ENSG00000006451 | v-ral simian leukemia viral oncogene homolog A (ras related) |
| Â | ENSG00000133101 | Cyclin A1 |
| Â | ENSG00000157404 | Similar to Mast/stem cell growth factor receptor precursor (SCFR) (Proto-oncogene tyrosine-protein kinase Kit)Ta |
| Â | ENSG00000175305 | Cyclin E2 |
| Â | ENSG00000168036 | Catenin (cadherin-associated protein), beta 1, 88Â kDa |
| Â | ENSG00000147889 | Cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) |
| Â | ENSG00000033800 | Protein inhibitor of activated STAT, 1 |
| Â | ENSG00000145675 | Phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| Â | ENSG00000044115 | Catenin (cadherin-associated protein), alpha 1, 102Â kDa |
| Â | ENSG00000156427 | Fibroblast growth factor 18 |
| Â | ENSG00000135766 | Egl nine homolog 1 (C. elegans) |
| Â | ENSG00000196591 | Histone deacetylase 2 |
| Â | ENSG00000138448 | Integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) |
| Â | ENSG00000108379 | Wingless-type MMTV integration site family, member 3 |
| Â | ENSG00000104290 | Frizzled homolog 3 (Drosophila) |
| Â | ENSG00000125084 | Wingless-type MMTV integration site family, member 1 |
| Â | ENSG00000102678 | Fibroblast growth factor 9 (glia-activating factor) |
| Â | ENSG00000185920 | Patched homolog 1 (Drosophila) |
| Â | ENSG00000111186 | Wingless-type MMTV integration site family, member 5B |
| Â | ENSG00000161958 | Fibroblast growth factor 11 |
| Â | ENSG00000128602 | Smoothened homolog (Drosophila) |
| Â | ENSG00000138795 | Lymphoid enhancer-binding factor 1 |
| Â | ENSG00000053747 | Laminin, alpha 3 |
| Â | ENSG00000056558 | TNF receptor-associated factor 1 |
| Â | ENSG00000131759 | Retinoic acid receptor, alpha |
| Â | ENSG00000099942 | v-crk sarcoma virus CT10 oncogene homolog (avian)-like |
| Â | ENSG00000139687 | Retinoblastoma 1 |
| Â | ENSG00000007968 | E2F transcription factor 2 |
Basal cell carcinoma | ENSG00000111186 | Wingless-type MMTV integration site family, member 5B |
| Â | ENSG00000128602 | Smoothened homolog (Drosophila) |
| Â | ENSG00000108379 | Wingless-type MMTV integration site family, member 3 |
| Â | ENSG00000138795 | Lymphoid enhancer-binding factor 1 |
| Â | ENSG00000168036 | Catenin (cadherin-associated protein), beta 1, 88Â kDa |
| Â | ENSG00000104290 | Frizzled homolog 3 (Drosophila) |
| Â | ENSG00000125084 | Wingless-type MMTV integration site family, member 1 |
| Â | ENSG00000143816 | Wingless-type MMTV integration site family, member 9A |