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Table 1 Number of genes and interaction pairs with high correlations between DNB and pathways.

From: Detecting early-warning signals of type 1 diabetes and its leading biomolecular networks by dynamical network biomarkers

Pathway name Time points The first DNB The second DNB
   DNB pathway pairs DNB pathway pairs
T cell receptor signaling pathway Critical point 93 32 493 96 7 327
  Disease onset point 89 105 677 93 107 844
NF-kappa B signaling pathway Critical point 94 28 372 96 9 425
  Disease onset point 92 87 588 89 87 705
Insulin signaling pathway Critical point 95 31 606 59 5 152
  Disease onset point 94 133 839 93 134 1023
  1. The column item "DNB" represents the number of genes in DNB which are highly correlated with the pathway in corresponding time point, the item "pathway" denotes the number of genes in the pathway which are highly correlated with the DNB in corresponding time point, and the item "pairs" means number of gene pairs which are highly correlated between genes separately in DNB and pathway in the corresponding time point.