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Table 2 Polymorphisms analyzed in PH and normolipemic populations by iPlex technology

From: A genetic variant in the LDLRpromoter is responsible for part of the LDL-cholesterol variability in primary hypercholesterolemia

  Polygenic hypercholesterolemia Controls  
Polymorphisms Zaragoza N=252 Barcelona N=127 AWHS N=98 Total N=477 AWHS N=525 P value
rs17242346 (g.3724G>A) 0.107 0.071 0.122 0.100 0.080 0.113
rs17242739 (g.3627C>A) 0.000 0.008 0.000 0.000 0.000 0.280
rs17248720 (g.3131C>T) 0.090 0.083 0.102 0.090 0.160 < 0.0001
rs17249120 (g.4440G>A) 0.004 0.000 0.020 0.003 0.010 0.082
  1. AWHS, Aragon Workers’ Health Study. Zaragoza, Barcelona and AWHS were the three hypercholesterolemic populations analyzed. Variables were compared using χ2 test. Genotype prevalences were estimated as observed proportions.