Table 4 The information of the 9 fetus hypermethylation DNA markers (FH) and 12 fetus hypomethylation DNA markers (FL)
From: DNA methylation study of fetus genome through a genome-wide analysis
Marker ID | Chromosomal locition | Associated gene |
|---|---|---|
FH1 | ChrM:1-542 | Mitochondrial DNA D-loop |
FH2 | ChrM:16,025-16,571 | Mitochondrial DNA D-loop |
FH3 | Chr19:40,628,281-40,629,300 | Free fatty acid receptor 2 (FFAR2) |
FH4 | Chr21:38,791,600-38,792,000 | Erythroblastosis virus E26 oncogene onmcogene homolog (ERG) |
FH5 | Chr7:2,411,800-2,412,100 | Carbohydrate (chondroitin 4) Sulfotransferase 12 (CHST12) |
FH6 | Chr12:6,528,400-6,528,750 | Intermediate filament family orphan 1 (IFFO1) |
FH7 | Chr9:129,579,800-129,580,000 | SH2 domain containing 3C (SH2D3C) |
FH8 | Chr17:36,717,500-36,717,900 | Keratin associated protein 16-1 (KRTAP16-1) |
FH9 | Chr19:1,019,900-1,020,200 | Histocompatibility (minor) HA-1 (HMHA1) |
FL1 | Chr7:27,130,100-27,130,600 | Homeobox A3 (HOXA3) |
FL2 | Chr11:62127350-62127700 | Echinoderm microtubule associated protein like 3 (EML3) |
FL3 | Chr3:32,835,500-32,835,800 | Tripartite motif containing 71, E3 ubiquitin protein ligase (TRIM71) |
FL4 | Chr7:27,185,300-27,185,650 | Homo sapiens homeobox A11 (HOXA11) |
FL5 | Chr6:10,664,250-10,664,600 | Homo sapiens glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (GCNT2) |
FL6 | Chr7:27,113,100-27,113,300 | Homo sapiens homeobox A2 (HOXA2) |
FL7 | Chr7:27,148,050-27,148,400 | Homeobox A5 (HOXA5) |
FL8 | Chr19:12,997,300-12,997,450 | Nuclear factor I/X (NFIX) (CCAAT-binding transcription factor) |
FL9 | Chr8:116,753,900-116,754,200 | Homo sapiens trichorhinophalangeal syndrome I (TRPS1) |
FL10 | Chr5:95,321,600-95,321,800 | Elongation factor, RNA polymerase II, 2 (ELL2) |
FL11 | Chr7:32,213,400-32,213,600 | Phosphodiesterase 1C, calmodulin-dependent (PDE1C) |
FL12 | Chr8:82,066,300-82,066,500 | Phosphoprotein associated with glycosphingolipid microdomains 1 (PAG1) |