Table 1 Summary of somatic SNVs
From: Whole-genome sequencing of matched primary and metastatic hepatocellular carcinomas
Categories | 441 | D430 | D473 | DD59 | ||||
|---|---|---|---|---|---|---|---|---|
Primary tumor | Metastasis | Primary tumor | Metastasis | Primary tumor | Metastasis | Primary tumor | Metastasis | |
# of somatic SNVs | 13,961 | 12,624 | 6,208 | 5,275 | 5,027 | 7,251 | 5,666 | 7,652 |
Synonymous | 24 | 26 | 19 | 13 | 13 | 11 | 5 | 13 |
Nonsense | 4 | 3 | 1 | 0 | 3 | 3 | 0 | 4 |
Missense | 74 | 69 | 23 | 18 | 22 | 36 | 33 | 45 |
Splice | 5 | 5 | 0 | 0 | 0 | 0 | 1 | 2 |
UTR | 84 | 76 | 43 | 30 | 37 | 44 | 44 | 57 |
Intron | 4,216 | 3,826 | 1,911 | 1,667 | 1,680 | 2,354 | 1,878 | 2,543 |
Intergenic | 9,554 | 8,619 | 4,211 | 3,547 | 3,272 | 4,803 | 3,705 | 4,988 |