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Figure 3 | BMC Medical Genomics

Figure 3

From: Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing

Figure 3

Low coverage samples have higher rates of C>T/G>A sequencing artefacts. For all FFPE samples (x-axis), values for coverage (blue) and the counts of C>T/G>A sequencing artefacts (red) are plotted on the same y-axis. There was an inverse correlation between coverage and C>T/G>A sequence artefacts (Spearman correlation, r = −0.24, p < 0.0001).

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BMC Medical Genomics

ISSN: 1755-8794

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