Table 2 Correlation between changes in SNORA12 gene expression and DNA methylation during infection with clinical characteristics of our study populations
|  | Healthy (n = 13) | Asthma (n = 16) | Both Groups | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | Expression | Methylation | Expression | Methylation | Expression | Methylation | ||||||
| Â | rs | p value | rs | p value | rs | p value | rs | p value | rs | p value | rs | p value |
Atopy | 0.16 | 0.59 | 0.12 | 0.69 | 0.20 | 0.47 | 0.17 | 0.53 | 0.26 | 0.18 | -0.09 | 0.63 |
FEV1 (% predicted) | -0.36 | 0.22 | 0.37 | 0.21 | 0.71 | 0.002 | 0.00 | 0.99 | 0.11 | 0.59 | 0.27 | 0.15 |
FEV1/FVC (L) | -0.57 | 0.04 | -0.09 | 0.76 | 0.43 | 0.10 | 0.23 | 0.39 | -0.12 | 0.55 | 0.29 | 0.13 |
PEF (L/min) | -0.08 | 0.80 | -0.08 | 0.79 | -0.13 | 0.64 | -0.04 | 0.88 | -0.08 | 0.68 | 0.00 | 1.00 |
Nasal Allergies | -0.22 | 0.50 | 0.39 | 0.21 | 0.08 | 0.78 | -0.02 | 0.95 | 0.13 | 0.51 | -0.17 | 0.39 |
Chronic Rhinosinusitis | 0.06 | 0.84 | 0.32 | 0.30 | -0.15 | 0.58 | -0.06 | 0.84 | -0.05 | 0.81 | 0.10 | 0.61 |
Albuterol use | n/a | n/a | n/a | n/a | -0.29 | 0.28 | 0.07 | 0.80 | -0.01 | 0.96 | -0.21 | 0.27 |