Figure 2From: Kinome and mRNA expression profiling of high-grade osteosarcoma cell lines implies Akt signaling as possible target for therapy Significantly affected pathways in osteosarcoma cells. Stacked bar chart depicting all significantly affected pathways as identified by gene expression profiling of osteosarcoma cell lines, showing percentages of up- (red), downregulated (green), not significantly altered genes (gray), and genes which were not present on the microarray (white). The –log(adjP) (−log(B-H) p-value) is plotted in orange, and is above 1.3 for adjP < 0.05.Back to article page