Table 9 Signaling pathways predicted to be regulated by altered miRNAs in ARDS
From: MicroRNA and mRNA expression profiling in rat acute respiratory distress syndrome
Pathway | Target number | Score |
|---|---|---|
Axon guidance | 57 | 31.92 |
ErbB signaling pathway | 37 | 19.04 |
MAPK signaling pathway | 80 | 17.12 |
Focal adhesion | 64 | 16.73 |
Regulation of actin cytoskeleton | 67 | 15.37 |
Colorectal cancer | 34 | 14.74 |
Chronic myeloid leukemia | 31 | 14.18 |
Wnt signaling pathway | 48 | 12.55 |
Glycan structures - biosynthesis 1 | 40 | 12.39 |
Glioma | 26 | 12.37 |
Pancreatic cancer | 28 | 11.05 |
Renal cell carcinoma | 26 | 9.49 |
TGF-beta signaling pathway | 31 | 9.33 |
Small cell lung cancer | 30 | 8.79 |
Long-term potentiation | 24 | 8.68 |
Oxidative phosphorylation | 6 | 8.34 |
Prostate cancer | 30 | 8.22 |
Circadian rhythm | 8 | 8.17 |
Arachidonic acid metabolism | 1 | 7.92 |
mTOR signaling pathway | 20 | 7.78 |
Antigen processing and presentation | 3 | 7.3 |
Adherens junction | 25 | 7.01 |
Acute myeloid leukemia | 21 | 6.96 |
T cell receptor signaling pathway | 29 | 6.00 |
Melanoma | 23 | 5.72 |
Tryptophan metabolism | 1 | 5.68 |
Endometrial cancer | 18 | 5.31 |
Glycosphingolipid biosynthesis - neo-lactoseries | 8 | 5.01 |
Type II diabetes mellitus | 16 | 4.82 |
Complement and coagulation cascades | 4 | 4.78 |
GnRH signaling pathway | 28 | 4.76 |
Insulin signaling pathway | 37 | 4.44 |
Melanogenesis | 28 | 4.40 |
Non-small cell lung cancer | 17 | 4.25 |