Figure 5

Cd44 modulates brown module hub gene expression. Peritoneal macrophages were isolated from C57BL/6 J and Cd44 ^-/- mice and treated in triplicate with media or media with 10 ng/ml LPS for 4 hours. Expression of Apbb1ip, Cd44, Evl, Fermt3, Gpsm3, Ncf2, Nckap1l, Plcg2, Tnf, Trpv2, and Was were normalized to Rpl4 and expressed relative to non-stimulated cells from C57BL/6 J mice (Panels A-K respectively). Genotype of the cells and treatment condition are indicated below the x-axis * indicates significant differences P < 0.05. Values represent mean ± sem.