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Table 4 The final mortality-predicting signature assessed using the Cox multivariate regression model

From: Identification of a prognostic signature for old-age mortality by integrating genome-wide transcriptomic data with the conventional predictors: the Vitality 90+ Study

  HR (95% CI) S.E. Z p
BMI 0.84 (0.77-0.91) 0.03 -4.22 <0.001
Frailty index (ref. = non-frail)     
Pre-frail 9.53 (2.70-33.6) 6.12 3.51 <0.001
Frail 17.7 (4.61-67.9) 12.14 4.19 <0.001
TMEM70 0.39 (0.18-0.84) 0.15 -2.40 0.017
GADD45B 2.60 (1.02-6.62) 1.24 2.00 0.045
NME4 1.77 (1.11-2.80) 0.41 2.42 0.015
MBP 0.58 (0.36-0.93) 0.14 -2.27 0.023
CHEK2 0.26 (0.12-0.55) 0.10 -3.50 <0.001
VKORC1 0.33 (0.18-0.59) 0.10 -3.68 <0.001
LRCH3 0.47 (0.25-0.87) 0.15 -2.40 0.016
LTA 2.09 (1.37-3.19) 0.45 3.43 0.001
SH2D1B 0.52 (0.36-0.76) 0.10 -3.44 0.001
  1. Abbreviations: BMI body-mass index, CI confidence interval, HR hazard ratio, S.E., standard error.