Skip to main content

Table 2 GO-BP overlap and similarity between N-of-1-pathways and FET Enrichment derived from RNA-Seq transcriptome profile of PTBP1-depleted neuronal cell line.

From: Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study

Curated GO-BP
classes
GO-BP Terms GO-BP
overlap
GO-BP
ITS ≥ 0.7*
Neuronal
specific
Cell cycle and DNA Replication GO:0006260: DNA Replication   
  GO:0051325: interphase   
  GO:0007067: mitosis    
  GO:0051329: interphase of mitotic cell cycle    
  GO:0010564: regulation of cell cycle process    
  GO:0033261: regulation of S phase    
  GO:0000279: M phase    
  GO:0000087: M phase of mitotic cell cycle    
  GO:0006974: response to DNA Damage Stimulus   
DNA repair GO:0006281: DNA Repair   
  GO:0006310: DNA recombination   
  GO:0006302: double-strand break repair    
Neuronal
transmission
GO:0007268: synaptic transmission  
  1. *GO-BP terms with Information Theoretic Similarities (ITS) ≥ 0.7 are considered highly related (Methods).