Table 2 GO-BP overlap and similarity between N-of-1-pathways and FET Enrichment derived from RNA-Seq transcriptome profile of PTBP1-depleted neuronal cell line.
Curated GO-BP classes | GO-BP Terms | GO-BP overlap | GO-BP ITS ≥ 0.7* | Neuronal specific |
|---|---|---|---|---|
Cell cycle and DNA Replication | GO:0006260: DNA Replication | ✓ | ||
GO:0051325: interphase | ✓ | |||
GO:0007067: mitosis | ✓ | |||
GO:0051329: interphase of mitotic cell cycle | ✓ | |||
GO:0010564: regulation of cell cycle process | ✓ | |||
GO:0033261: regulation of S phase | ✓ | |||
GO:0000279: M phase | ✓ | |||
GO:0000087: M phase of mitotic cell cycle | ✓ | |||
GO:0006974: response to DNA Damage Stimulus | ✓ | |||
DNA repair | GO:0006281: DNA Repair | ✓ | ||
GO:0006310: DNA recombination | ✓ | |||
GO:0006302: double-strand break repair | ✓ | |||
Neuronal transmission | GO:0007268: synaptic transmission | ✓ | ✓ |