Figure 2
From: Integrated analysis of microRNA-target interactions with clinical outcomes for cancers
Selecting significant miRNA-mRNA pairs from HL:LH (high miRNA & low mRNA expression group vs. low miRNA & high mRNA expression group) type. Selecting significant miRNA-mRNA pairs from HL:LH (high miRNA & low mRNA expression group vs. low miRNA & high mRNA expression group) type. A. Distribution of significances by Log-rank test with HL:LH type in ovarian cancer. The dashed line indicates the threshold that the false discovery ratio is 0.01. B. The scatter plot of expression values for miR-98 and PLAGL1 pair among miRNA and mRNA pairs. Each point indicates a patient with HL:LH expression pattern. C. The heatmap of average expression values of miRNA and mRNAs for all significant pairs. Each cell indicates average expression value of a miRNA or mRNA in a group (i.e. HL or LH)