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Table 4 Approved and clinical targets for seven complex diseases

From: Identification of novel therapeutics for complex diseases from genome-wide association data

PH

AT

NAT

CT

NCT

T2D

45

41

65

62

T1D

57

55

73

72

HT

71

68

43

40

RA

55

53

59

54

CD

93

93

135

135

CAD

63

61

80

76

BD

37

36

44

44

Unique sum

291

277

334

318

  1. Abbreviations - PH - Phenotypes; AT - Approved Targets; NAT - Novel Approved Targets; CT - Clinical Targets; NCT - Novel Clinical Targets; T2D - Type 2 Diabetes; T1D - Type 1 Diabetes; HT - Hypertension; RA - Rheumatoid Arthritis; CD - Crohn's Disease; CAD - Coronary Artery Disease; BD - Bipolar Disorder.
  2. Predicted therapeutic targets targeted by FDA-approved drugs and drugs in clinical trials.