Table 1 Top 20 candidate disease-related genes identified by PageRank method with significant analysis from PIN, TSN, WPIN, WTSN, for colon cancer, respectively.
WTSN | WPIN | TSN | PIN | ||||
|---|---|---|---|---|---|---|---|
Genes | In GeneSigDB | Genes | In GeneSigDB | Genes | In GeneSigDB | Genes | In GeneSigDB |
CDH1 | yes | APC | yes | NR3C1 | yes | UBC | no |
FAS | yes | CDH1 | yes | MLH1 | yes | ELAVL1 | yes |
CD44 | yes | FAS | yes | CDH1 | yes | SUMO2 | yes |
THBS1 | yes | CD44 | yes | CDKN2A | yes | MYC | yes |
TIMP3 | yes | THBS1 | yes | ATM | no | GRB2 | no |
GSTP1 | yes | STK11 | no | FAS | yes | SUMO1 | yes |
CREBBP | yes | GSTP1 | yes | MGMT | no | SNCA | no |
STK11 | no | UBC | no | THBS1 | yes | ESR1 | yes |
HDAC1 | yes | ALX4 | no | CD44 | yes | GABARAPL2 | no |
UBC | no | HRK | yes | RASSF1 | yes | TP53 | yes |
NCL | yes | TIMP3 | yes | STK11 | no | YWHAZ | yes |
CCND1 | yes | SRC | yes | DAPK1 | yes | GABARAPL1 | yes |
PRKDC | yes | NCL | yes | CHFR | no | GABARAP | no |
SFN | yes | CREBBP | yes | GSTP1 | yes | TRAF6 | yes |
ELAVL1 | yes | HDAC1 | yes | UBC | no | RAD23A | yes |
TGM2 | yes | SFRP1 | yes | TIMP3 | yes | EP300 | no |
FYN | no | ELAVL1 | yes | HSP90AA1 | yes | EGFR | yes |
FN1 | yes | CCND1 | yes | TP53 | yes | SRC | yes |
ACTR3 | yes | PRKDC | yes | SFRP1 | yes | YWHAG | yes |
MMP14 | yes | FYN | no | PML | yes | ESR2 | no |