Table 1 Performance of EvoD, PolyPhen-2 and SIFT when analyzing PharmGKB variants.
From: Evolutionary Diagnosis of non-synonymous variants involved in differential drug response
| Â | Diagnosis Rate | Â | |||
|---|---|---|---|---|---|
Method | TNR | FPR | FNR | TPR | Balanced Accuracy |
EvoD | 49% | 51% | 61% | 39% | 44% |
PolyPhen-2 | 60% | 40% | 55% | 45% | 52% |
SIFT | 46% | 54% | 47% | 53% | 50% |