Figure 4
From: Novel therapeutics for coronary artery disease from genome-wide association study data
Comparison of therapeutic targets and candidate genes obtained after reanalysing WTCCC-GWAS data in 5-module study vs our previous 2-module study. A) Comparison of therapeutic targets for CAD obtained in the two different studies by utilizing different number of bioinforamtic databases to reanalyse the same WTCCC-GWAS data. In this study, 79 therapeutic targets were replicated from the previous study (Grover et al, 2014), and 113 additional therapeutic targets were identified; B) Comparison of predicted candidate genes obtained by reanalysing the same WTCCC-GWAS data in the two different studies (Green crosshatched portion - Ballouz et al, 2011, Yellow crosshatched portion - Ballouz et al, 2014). In our recently published study for CAD (Ballouz et al 2014), 204 candidate genes were replicated from the previous study (Ballouz et al, 2011) and 443 additional candidate genes were identified (Ballouz et al, 2014). Abbreviation - CAD: Coronary Artery Disease.