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Table 3 Binary classification of targets present in six search spaces

From: Novel therapeutics for coronary artery disease from genome-wide association study data

 

Known Drug Targets

Novel Drug Targets

CAD candidates

T.P. = 8

F.P. = 184

CAD non-candidates

F.N. = 4

T.N. = 4,519

Σ 4,715

  1. Binary classification of therapeutic targets considering six thresholds based on therapeutic targets present in six search spaces constructed in weakly significant data set (WS). Abbreviations: CAD - Coronary Artery Disease; TP - True Positives; FP - False Positives; TN - True Negatives; FN - False Negatives.