Table 3 Statistics of disease-associated SNPs based on Functional Categories
Functional classification | Number of SNPs | Number of Disease-associated SNPs | Coverage Ratio | P-value |
|---|---|---|---|---|
Missense & Stop-gain (PTM-SNP) | 179,325 | 186 | 0.00114 | 2.72E-67 |
NearGene-5 | 744,086 | 251 | 0.00033 | 7.59E-13 |
UTR-3: MirSNP | 414,510 | 151 | 0.00036 | 2.76E-10 |
UTR-3 | 513,249 | 170 | 0.00033 | 1.61E-08 |
NearGene-3 | 189,105 | 71 | 0.00037 | 2.54E-06 |
UTR-5 | 80,250 | 35 | 0.00043 | 3.33E-05 |
Cds-synon | 312,479 | 100 | 0.00032 | 4.54E-05 |
Missense & Stop-gain (Non PTM-SNP) | 361,401 | 95 | 0.00026 | 0.014 |
Intergenic | 20,492,263 | 4,357 | 0.00021 | 0.136 |
Frameshift | 30,578 | 5 | 0.00016 | 0.768 |
Intron | 19,248,959 | 3,678 | 0.00019 | 0.999 |
Total SNPs | 41,740,143 | 8,771 | 0.00021 | - |