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Figure 4 | BMC Medical Genomics

Figure 4

From: Integrated differential transcriptome maps of Acute Megakaryoblastic Leukemia (AMKL) in children with or without Down Syndrome (DS)

Figure 4

Biological model of the transcriptome depicting progressive changes from MK to TMD then to DS AMKL. Downward pointing arrow indicates the repression of genes involved in MK differentiation; upward pointing arrow indicates the over-expression of potential molecular markers of progression to AMKL. Value: mean gene expression value normalized across all the pool samples. ยงObserved both in DS and non-DS AMKL.

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