Table 6 Genomic segments significantly over- or under-expressed
a) DS AMKL vs. TMD | |||||
Chr a and location | Segment start b | Segment end b | 'A'/'C' ratio | q-value | Genes in the segment c |
Over-expressed segments | |||||
chr2 2q31.3 | 182,000,001 | 182,500,000 | 2.20 | 0.00045 | ITGA4 + Hs.660611- Hs.658786+ CERKL+ Hs.72981+ |
chr8 8q21.3 | 91,750,001 | 92,250,000 | 1.40 | 0.00051 | NECAB1 + Hs.743640+ LOC100127983+ TMEM55A+ LOC100506365- OTUD6B+ LRRC69+ |
b) TMD vs. normal MK | |||||
Chr and location | Segment start | Segment end | 'C'/'D' ratio | q-value | Genes in the segment |
Over-expressed segments | |||||
chr3 3p26.2 | 3,500,001 | 4,000,000 | 28.00 | 0.00006 | Hs.241414+ d Hs.587205+ LRRN1 + Hs.128128+ |
chr15 15q26.2 | 96,750,001 | 97,250,000 | 19.86 | 0.00000 | Hs.677040+ d Hs.661950+ d NR2F2-AS1 + NR2F2- Hs.592015+ |
c) TMD vs. normal CB MK | |||||
Chr and location | Segment start | Segment end | 'C'/'E' ratio | q-value | Genes in the segment |
chr3 3q22.1 | 130,000,001 | 130,500,000 | 75.97 | 0.00015 | COL6A5 + COL6A6 + Hs.596709+ Hs.596805+ PIK3R4- |