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Table 6 Genomic segments significantly over- or under-expressed

From: Integrated differential transcriptome maps of Acute Megakaryoblastic Leukemia (AMKL) in children with or without Down Syndrome (DS)

a) DS AMKL vs. TMD
Chr a and location Segment start b Segment end b 'A'/'C' ratio q-value Genes in the segment c
Over-expressed segments
chr2 2q31.3 182,000,001 182,500,000 2.20 0.00045 ITGA4 + Hs.660611- Hs.658786+ CERKL+ Hs.72981+
chr8 8q21.3 91,750,001 92,250,000 1.40 0.00051 NECAB1 + Hs.743640+ LOC100127983+ TMEM55A+ LOC100506365- OTUD6B+ LRRC69+
b) TMD vs. normal MK
Chr and location Segment start Segment end 'C'/'D' ratio q-value Genes in the segment
Over-expressed segments
chr3 3p26.2 3,500,001 4,000,000 28.00 0.00006 Hs.241414+ d Hs.587205+ LRRN1 + Hs.128128+
chr15 15q26.2 96,750,001 97,250,000 19.86 0.00000 Hs.677040+ d Hs.661950+ d NR2F2-AS1 + NR2F2- Hs.592015+
c) TMD vs. normal CB MK
Chr and location Segment start Segment end 'C'/'E' ratio q-value Genes in the segment
chr3
3q22.1
130,000,001 130,500,000 75.97 0.00015 COL6A5 + COL6A6 + Hs.596709+ Hs.596805+ PIK3R4-