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Table 2 Clinical information of clinically nonfunctional pituitary adenoma and control pituitary samples

From: Heterogeneity analysis of the proteomes in clinically nonfunctional pituitary adenomas

Groups Sample ID Sex/Age Clinical information Immunohistochemistry
NF-NFPA T164 M/35 Non-functional, visual loss, 3 × 3.5 × 4 cm. Partial hypopituitarism Neg.
T217 M/39 Non-functional Neg.
T219 M/68 Non-functional, 1.9 × 2.3 × 2.2 cm, invasion of the right cavernous sinus Neg.
LH-NFPA T208 F/47 Non-functional, 2 × 2 × 2 cm LH 1-2+
T204 M/47 Non-functional LH 3+
T237 F/40 Non-functional, right cavernous sinus extension LH 2+
FSH-NFPA T57 F/59 Non-functional, 2 × 3 cm FSH 1+
T89 M/62 Non-functional, 2 × 2.3 × 2.3 cm FSH 2+
T77 M/67 Non-functional, 2 × 2.2 × 2.4 cm, questionable cavernous sinus FSH 2+
LH/FSH-NFPA T65 F/54 Non-functional, 4 × 4 × 4 cm, cavernous sinus invasion LH 2+, FSH 1+
T138 M/60 Non-functional, 2.9 × 3.1 × 3.5 cm LH 2+, FSH 2+
T185 M/66 Non-functional, 2.8 ×, 2 × 2.4 cm. Bilateral cavernous sinus invasion LH 2-3+, FSH 2-3+
Control pituitary (Con) C2 M/27 Black, none DNT
C3 F/40 White, Multiple toxic compounds. Blood: HepBb (+), HepC (+), HIV (−) DNT
C4 M/45 White, Drowning. Blood alcohol = 3.1 g/L; no other drugs detected. Blood: HepB (+), HepC (+), HIV (−) DNT
C5 M/36 White, Multiple toxic materials. Blood alcohol = 0.5 g/L. Blood: HepB (+), HepC (−), HIV (−) DNT
C7 F/34 Black, Gunshot wound to chest. Blood alcohol = 0.3 g/L; no drugs. Blood: HepB (+), HepC (−), HIV (−) DNT
C8 F White, 15 h gunshot wound to head. No drugs or alcohol. Blood: HepB (−), HepC (−), HIV (−) DNT
C9 M/55 White, 12 h gunshot wound to chest. No alcohol or drugs. Blood: HepB (−), HepC (−), HIV (−) DNT
C10 F/47 White, Smoke inhalation. No drugs or alcohol. Numerous amylacea present in brain. Early autolytic changes to brain. Blood: HepB (−), HepC (+), HIV (−) DNT
  1. Note: All those hormones (ACTH, LH, FSH, PRL, GH, and TSH) were immunohistochemisty-tested in each pituitary adenoma tissue. Neg. = Immunohistochemical stains for ACTH, LH, FSH, PRL, GH, and TSH were negative. LH+ = nonfunctional pituitary adenoma that expressed leuteinizing hormone, or lutropin; FSH+ = nonfunctional pituitary adenoma that expressed follicle-stimulating hormone, or follitropin; FSH+, LH+ = nonfunctional pituitary adenoma that expressed both follicle-stimulating hormone and leuteinizing hormone. Adenomas were graded blindly by a neuropathologist (from 0–4) for the intensity of staining for each peptide hormone. NFPA = nonfunctional pituitary adenoma. DNT = do not test.