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Table 1 Characteristics of the study population treated with and without statin

From: Effects of statin on circulating microRNAome and predicted function regulatory network in patients with unstable angina

  Whole blood   Plasma  
  Control(n = 10) Stain(n = 10) p value Control(n = 5) Stain(n = 5) p value
General data       
  Sex, M/F (4/6) (5/5) >0.99 (3/2) (1/4) 0.524
  Age(yrs) 59 ± 7.9 56 ± 7.6 0.394 59 ± 4.2 64 ± 9.9 0.343
  SBP(mm Hg) 135 ± 15.1 131 ± 15.6 0.889 131 ± 12.1 128 ± 16.4 0.758
  DBP(mm Hg) 80 ± 7.1 82 ± 12.4 0.591 78 ± 8.1 75 ± 11.2 0.669
Medical history       
  Hypertension(%) 90(9/10) 80(8/10) >0.99 60(3/5) 100(5/5) 0.444
  Diabetes(%) 0(0/10) 0(0/10) >0.99 20(1/5) 20(1/5) >0.99
  Hyperlipaemia(%) 30(3/10) 50(5/10) 0.649 60(3/5) 100(5/5) 0.444
  Cerebral vascular disease (%) 0(0/10) 0(0/10) >0.99 0(0/5) 0(0/5) >0.99
  Smoking(%) 20(2/10) 0(0/10) 0.474 40(2/5) 0(0/5) 0.444
Laboratory test       
  Glucose(mmol/l) 5.4 ± 1.2 5.2 ± 1.4 0.796 4.8 ± 0.6 5.1 ± 0.6 0.526
  LDL cholesterol (mmol/l) 2.5 ± 0.9 2.2 ± 0.9 0.577 2.6 ± 0.7 2.4 ± 0.4 0.605
  HDl cholesterol (mmol/l) 1.0 ± 0.1 1.1 ± 0.3 0.314 1.2 ± 0.3 0.8 ± 0.1 0.034*
  TC (mmol/l) 4.3 ± 0.9 4.0 ± 1.1 0.364 4.3 ± 0.5 3.9 ± 0.6 0.462
  TG(mmol/l) 1.3 ± 0.6 1.2 ± 0.7 0.496 1.6 ± 0.2 1.6 ± 0.3 0.897
  Creatinine(mg/dl) 60.7 ± 13.5 62.5 ± 18.8 0.781 76.2 ± 13.5 62.0 ± 20.2 0.781
  alt(u/l) 28.9 ± 16.8 20.7 ± 9.2 0.211 21.6 ± 17.2 17.6 ± 5.3 0.616
  ast(u/l) 23.4 ± 11.2 18.1 ± 4.27 0.224 18.8 ± 8.3 18.4 ± 2.3 0.897
Medication       
  Aspirin(%) 30(3/10) 50(5/10) 0.649 40(2/5) 60(3/5) >0.99
  Clopidogrel(%) 30(3/10) 30(3/10) >0.99 20(1/5) 60(3/5) 0.524
  Calcium antagonists (%) 40(4/10) 20(2/10) 0.628 40(2/5) 20(1/5) >0.99
  ACEI/ARBs(%) 50(5/10) 20(2/10) 0.349 0(0/5) 20(1/5) >0.99
  β-Blockers(%) 20(2/10) 40(4/10) 0.628 40(2/5) 40(2/5) >0.99
  1. SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TC, total cholesterol; TG, triglyceride; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ACEI, angiotensin-converting enzyme inhibitor; and ARB, angiotensin receptor blocker. Comparisons between groups were performed with Student’s t test or Mann–Whitney U test for continuous variables and with the Fischer exact test or x2 test for categorical variables.
  2. *p<0.05 versus control.