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Table 1 Characteristics of the study population treated with and without statin

From: Effects of statin on circulating microRNAome and predicted function regulatory network in patients with unstable angina

 

Whole blood

 

Plasma

 
 

Control(n = 10)

Stain(n = 10)

p value

Control(n = 5)

Stain(n = 5)

p value

General data

      

  Sex, M/F

(4/6)

(5/5)

>0.99

(3/2)

(1/4)

0.524

  Age(yrs)

59 ± 7.9

56 ± 7.6

0.394

59 ± 4.2

64 ± 9.9

0.343

  SBP(mm Hg)

135 ± 15.1

131 ± 15.6

0.889

131 ± 12.1

128 ± 16.4

0.758

  DBP(mm Hg)

80 ± 7.1

82 ± 12.4

0.591

78 ± 8.1

75 ± 11.2

0.669

Medical history

      

  Hypertension(%)

90(9/10)

80(8/10)

>0.99

60(3/5)

100(5/5)

0.444

  Diabetes(%)

0(0/10)

0(0/10)

>0.99

20(1/5)

20(1/5)

>0.99

  Hyperlipaemia(%)

30(3/10)

50(5/10)

0.649

60(3/5)

100(5/5)

0.444

  Cerebral vascular disease (%)

0(0/10)

0(0/10)

>0.99

0(0/5)

0(0/5)

>0.99

  Smoking(%)

20(2/10)

0(0/10)

0.474

40(2/5)

0(0/5)

0.444

Laboratory test

      

  Glucose(mmol/l)

5.4 ± 1.2

5.2 ± 1.4

0.796

4.8 ± 0.6

5.1 ± 0.6

0.526

  LDL cholesterol (mmol/l)

2.5 ± 0.9

2.2 ± 0.9

0.577

2.6 ± 0.7

2.4 ± 0.4

0.605

  HDl cholesterol (mmol/l)

1.0 ± 0.1

1.1 ± 0.3

0.314

1.2 ± 0.3

0.8 ± 0.1

0.034*

  TC (mmol/l)

4.3 ± 0.9

4.0 ± 1.1

0.364

4.3 ± 0.5

3.9 ± 0.6

0.462

  TG(mmol/l)

1.3 ± 0.6

1.2 ± 0.7

0.496

1.6 ± 0.2

1.6 ± 0.3

0.897

  Creatinine(mg/dl)

60.7 ± 13.5

62.5 ± 18.8

0.781

76.2 ± 13.5

62.0 ± 20.2

0.781

  alt(u/l)

28.9 ± 16.8

20.7 ± 9.2

0.211

21.6 ± 17.2

17.6 ± 5.3

0.616

  ast(u/l)

23.4 ± 11.2

18.1 ± 4.27

0.224

18.8 ± 8.3

18.4 ± 2.3

0.897

Medication

      

  Aspirin(%)

30(3/10)

50(5/10)

0.649

40(2/5)

60(3/5)

>0.99

  Clopidogrel(%)

30(3/10)

30(3/10)

>0.99

20(1/5)

60(3/5)

0.524

  Calcium antagonists (%)

40(4/10)

20(2/10)

0.628

40(2/5)

20(1/5)

>0.99

  ACEI/ARBs(%)

50(5/10)

20(2/10)

0.349

0(0/5)

20(1/5)

>0.99

  β-Blockers(%)

20(2/10)

40(4/10)

0.628

40(2/5)

40(2/5)

>0.99

  1. SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TC, total cholesterol; TG, triglyceride; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ACEI, angiotensin-converting enzyme inhibitor; and ARB, angiotensin receptor blocker. Comparisons between groups were performed with Student’s t test or Mann–Whitney U test for continuous variables and with the Fischer exact test or x2 test for categorical variables.
  2. *p<0.05 versus control.