Figure 1
From: BMP2 response pattern in human lung fibroblasts predicts outcome in lung adenocarcinomas
Response of lung stromal fibroblasts (CCL-171) to BMP2 stimulation. Biologically independent duplicate samples of non-stimulated (Mock) and BMP2 stimulated CCL-171 cells for 24h were profiled for gene expression changes using HEEBO- microarrays. After filtering for data quality as described in the methods section, filtering for data distribution (SD > =0.7) and zero-transformation by the mean of the non-stimulated samples unsupervised hierarchical clustering was performed and the data were displayed in a heatmap. The genes are presented in rows and experiments in columns. Red and green correspond to up- and down-regulation, respectively. The intensity of the color reflects the magnitude of the change in the expression level as depicted on a color key. The genes of interest and the CCL-171 derived BMP2 signature are indicated.