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Table 3 Performance of bronchoscopy, classifier, and the combined procedures in the test set

From: Derivation of a bronchial genomic classifier for lung cancer in a prospective study of patients undergoing diagnostic bronchoscopy

Category

Bronchoscopy

Classifier *

Classifier & bronchoscopy combined

N, total

163

123

163

N, Lung cancer

78

38

78

N, Benign disease

85

85

85

Sensitivity (95% CI)

51% (40-62%)

92% (78-98%)

96% (89-99%)

Specificity (95% CI)

100% (95-100%)

53% (42-63%)

53% (42-63%)

NPV (95% CI)

69% (60-77%)

94% (83-98%)

94% (83-98%)

PPV (95% CI)

100% (90-100%)

47% (36-58%)

65% (56-73%)

  1. *The performance of the classifier was evaluated in patients in which bronchoscopy did not result in a finding of cancer (n = 123).