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Table 5 Comparison of biopsy and screening results between NGS (Group A) and aCGH (Group B) in Phase II study

From: Randomized comparison of next-generation sequencing and array comparative genomic hybridization for preimplantation genetic screening: a pilot study

Parameters

NGS

aCGH

p

Total number of blastocysts

447

452

 

Biopsied blastocysts % (n)

93.5 % (418)

94.5 % (427)

0.643a

Euploid % (n)

38.9 % (163)

40.0 % (171)

0.809a

Aneuploid % (n)

59.6 % (249)

57.8 % (247)

0.661a

No signal % (n)

1.4 % (6)

2.1 % (9)

0.604b

  1. aby Chi-square analysis
  2. bby Fisher’s exact test