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Table 5 Top 10 up and down regulated differentially expressed genes in neutrophils in juvenile idiopathic arthritis with active status compared with in juvenile rheumatoid arthritis with clinical remission on medicine status

From: RNA sequencing from human neutrophils reveals distinct transcriptional differences associated with chronic inflammatory states

Gene symbol Base Mean_all Base Mean_AD Base Mean_CRM p value Fold change (AD vs CRM)
LOC100652901 2.584163876 4.893556785 0.274770967 0.028780503 17.80958462
APOBEC3B 83.15003176 153.1234541 13.17660941 0.046805157 11.620854
AASS 4.098483224 7.372653548 0.824312901 0.03030685 8.943998745
ELF5 5.151781844 8.903353288 1.400210399 0.009241724 6.358582465
COL4A3 4.238990844 7.254099279 1.223882409 0.035842855 5.927121121
ZNF772 8.041388866 13.0963408 2.986436929 0.027467532 4.385272857
PAM 185.1146538 300.6639308 69.56537684 0.035123308 4.3220341
RNU5A-1 13.32454668 21.2148916 5.434201748 0.009970308 3.903957304
CEACAM19 12.44161404 19.01848534 5.864742738 0.035882882 3.242850743
LOC100128028 9.96808427 15.18599541 4.75017313 0.038699912 3.196935142
IFI44 1090.259979 234.9096707 1945.610288 0.034410811 −8.282376295
OAS3 3312.067396 599.3511189 6024.783673 0.012004606 −10.05217723
OAS2 1177.854158 208.429431 2147.278884 0.045495414 −10.30218657
PGM5 60.33985892 10.55582037 110.1238975 0.027057445 −10.43252856
IFI44L 1221.349953 203.5852067 2239.1147 0.013271076 −10.99841554
TIAF1 2.970579096 0.413585692 5.5275725 0.029142879 −13.36499935
OAS1 675.8399068 93.42104659 1258.258767 0.00911317 −13.46868626
LY6E 887.4348129 108.049892 1666.819734 0.022952433 −15.42638964
LILRB5 3.535606771 0.413585692 6.657627849 0.044736858 −16.09733601
FAM21B 36.36690516 4.133439531 68.60037079 0.022509698 −16.59643749