Table 5 Top 10 up and down regulated differentially expressed genes in neutrophils in juvenile idiopathic arthritis with active status compared with in juvenile rheumatoid arthritis with clinical remission on medicine status
Gene symbol | Base Mean_all | Base Mean_AD | Base Mean_CRM | p value | Fold change (AD vs CRM) |
|---|---|---|---|---|---|
LOC100652901 | 2.584163876 | 4.893556785 | 0.274770967 | 0.028780503 | 17.80958462 |
APOBEC3B | 83.15003176 | 153.1234541 | 13.17660941 | 0.046805157 | 11.620854 |
AASS | 4.098483224 | 7.372653548 | 0.824312901 | 0.03030685 | 8.943998745 |
ELF5 | 5.151781844 | 8.903353288 | 1.400210399 | 0.009241724 | 6.358582465 |
COL4A3 | 4.238990844 | 7.254099279 | 1.223882409 | 0.035842855 | 5.927121121 |
ZNF772 | 8.041388866 | 13.0963408 | 2.986436929 | 0.027467532 | 4.385272857 |
PAM | 185.1146538 | 300.6639308 | 69.56537684 | 0.035123308 | 4.3220341 |
RNU5A-1 | 13.32454668 | 21.2148916 | 5.434201748 | 0.009970308 | 3.903957304 |
CEACAM19 | 12.44161404 | 19.01848534 | 5.864742738 | 0.035882882 | 3.242850743 |
LOC100128028 | 9.96808427 | 15.18599541 | 4.75017313 | 0.038699912 | 3.196935142 |
IFI44 | 1090.259979 | 234.9096707 | 1945.610288 | 0.034410811 | −8.282376295 |
OAS3 | 3312.067396 | 599.3511189 | 6024.783673 | 0.012004606 | −10.05217723 |
OAS2 | 1177.854158 | 208.429431 | 2147.278884 | 0.045495414 | −10.30218657 |
PGM5 | 60.33985892 | 10.55582037 | 110.1238975 | 0.027057445 | −10.43252856 |
IFI44L | 1221.349953 | 203.5852067 | 2239.1147 | 0.013271076 | −10.99841554 |
TIAF1 | 2.970579096 | 0.413585692 | 5.5275725 | 0.029142879 | −13.36499935 |
OAS1 | 675.8399068 | 93.42104659 | 1258.258767 | 0.00911317 | −13.46868626 |
LY6E | 887.4348129 | 108.049892 | 1666.819734 | 0.022952433 | −15.42638964 |
LILRB5 | 3.535606771 | 0.413585692 | 6.657627849 | 0.044736858 | −16.09733601 |
FAM21B | 36.36690516 | 4.133439531 | 68.60037079 | 0.022509698 | −16.59643749 |