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Table 1 List of most highly ranked genes based on Betweenness Centrality (BC) score

From: Gene expression profiling of the human natural killer cell response to Fc receptor activation: unique enhancement in the presence of interleukin-12

Rank Gene Betweenness Centrality Score
1 IL21R 0.0921779
2 FASLG 0.0612643
3 IRF4 0.0545417
4 STAT4 0.0455257
5 TNFRSF4 0.0438375
6 IL2RB 0.0244015
7 CCR5 0.0233243
8 P2RX5 0.0203641
9 SLC7A5 0.0195173
10 BATF3 0.0192476
11 TNFRSF9 0.0188821
12 TBX21 0.0176988
13 IFNG 0.0171686
14 IRF1 0.0171325
15 ACAP1 0.0170313
16 CXCR6 0.0149211
17 TRIB1 0.0146721
18 EBI3 0.0141001
19 NFKB2 0.0134729
20 EIF4A1 0.0132968
  1. BC scores were calculated via the PAJEK algorithm (22), and are presented in decreasing order within the integrated network. A higher BC score indicates that a given gene is highly interconnected with other genes and gene products