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Table 1 List of most highly ranked genes based on Betweenness Centrality (BC) score

From: Gene expression profiling of the human natural killer cell response to Fc receptor activation: unique enhancement in the presence of interleukin-12

Rank

Gene

Betweenness Centrality Score

1

IL21R

0.0921779

2

FASLG

0.0612643

3

IRF4

0.0545417

4

STAT4

0.0455257

5

TNFRSF4

0.0438375

6

IL2RB

0.0244015

7

CCR5

0.0233243

8

P2RX5

0.0203641

9

SLC7A5

0.0195173

10

BATF3

0.0192476

11

TNFRSF9

0.0188821

12

TBX21

0.0176988

13

IFNG

0.0171686

14

IRF1

0.0171325

15

ACAP1

0.0170313

16

CXCR6

0.0149211

17

TRIB1

0.0146721

18

EBI3

0.0141001

19

NFKB2

0.0134729

20

EIF4A1

0.0132968

  1. BC scores were calculated via the PAJEK algorithm (22), and are presented in decreasing order within the integrated network. A higher BC score indicates that a given gene is highly interconnected with other genes and gene products
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BMC Medical Genomics

ISSN: 1755-8794

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