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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Identification of potential mutations and genomic alterations in the epithelial and spindle cell components of biphasic synovial sarcomas using a human exome SNP chip

Fig. 3

STRING network analysis reveals a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations. The network has been simplified for clear illustration of genes of interest. Stronger associations are represented by thicker lines. The significant genes were mainly TP53, AKT1, SRC, EGF, EGFR, PIK3CG, EP300 and FYN, and enriched functional categories included focal adhesion, cytokine–cytokine receptor interactions, the ERBB signaling pathway, the cell cycle, adherens junctions and the JAK–STAT signaling pathway

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BMC Medical Genomics

ISSN: 1755-8794

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