Fig. 2

Molecular dissection of breast cancer tumours in function of age. Average hierarchical clustering and heatmap showing the segregation of three age groups as a function of 24 GES scores. a Whole cohort. b Caucasian cohort. These figures are illustrations of table 4 statistical analyses. First row presents the three age groups: ≤ 40 years (a, n = 345; b, n = 166) (sky blue), 40 < x < 70 years (a, n = 1667; b, n = 974) (medium blue) and ≥ 70 years (a, n = 366; b, n = 273) (dark blue), from left to right. Other rows, from top to bottom, present PAM50 GES subtyping (basal-like (red); HER2-E (purple); luminal A (dark blue); luminal B (sky blue); normal breast-like (green); unclassified (yellow)) and GES scores in function of age (green: low score; red and green grid pattern: intermediate score; red: high score; sky blue: not significant or not interpretable)