Skip to main content

Table 4 AUC under the holdout approach and different genotype-based predictors learned using only the 100 top SNPs

From: A comparison of genomic profiles of complex diseases under different models

Disease

NBC

sSVM

AdaBoostM1

C4.5

20RF

lasso

RR

LR GRS

LR wGRS

GLM AIC

BD

0.53

0.551

0.552

0.524

0.535

0.552

0.553

0.523

0.534

0.551

CAD

0.573

0.582

0.56

0.532

0.574

0.566

0.569

0.556

0.568

0.567

HT

0.541

0.543

0.545

0.538

0.539

0.559

0.548

0.527

0.535

0.553

IBD

0.568

0.574

0.587

0.522

0.557

0.585

0.587

0.56

0.569

0.577

RA

0.651

0.715

0.734

0.694

0.689

0.725

0.73

0.614

0.638

0.736

T1D

0.675

0.79

0.777

0.747

0.771

0.777

0.79

0.669

0.686

0.793

T2D

0.566

0.569

0.565

0.541

0.566

0.575

0.571

0.566

0.576

0.556

  1. The highest AUC for each disease is shown in boldface