Skip to main content
Fig. 3 | BMC Medical Genomics

Fig. 3

From: Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses

Fig. 3

Identification of molecular drivers of differential responses to HDM in CD4 T cells. Differentially expressed genes/molecular drivers were identified between the response patterns of: a/c HDM-sensitized atopics with asthma versus HDM-nonsensitized controls; b/d HDM-sensitized atopics without asthma versus HDM-nonsensitized controls. Data analysis was performed by LIMMA (a, b) and upstream regulator analysis (c, d). The dashed horizontal line in figs a, b indicates FDR <0.05. Drivers in red are predicted to be activated and those in blue are inhibited

Back to article page